Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 5/20 | 0.48 |
| ▸ | PDCD1LG2 | Q9BQ51 | 6/20 | 0.44 |
| ▸ | CD274 | Q9NZQ7 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31552850 | 0.81 | NISCH (0.49) | NISCHPDCD1LG2CD274 | |
| SCHEMBL12765025 | 0.78 | NISCH (0.53) | NISCHPDCD1LG2CD274 | |
| SCHEMBL18824619 | 0.74 | LMNA (0.53) | NISCHLMNARECQL | |
| SCHEMBL22743021 | 0.71 | NISCH (0.46) | NISCHPDCD1LG2CD274 | |
| SCHEMBL31552847 | 0.71 | NISCH (0.46) | NISCHPDCD1LG2CD274 | |
| SCHEMBL11285481 | 0.71 | NISCH (0.54) | NISCHLMNARECQL | |
| SCHEMBL4818139 | 0.69 | NISCH (0.62) | NISCHPDCD1LG2CD274 | |
| Hydrochloric Acid SCHEMBL4913189 | 0.68 | NISCH (0.61) | NISCHPDCD1LG2CD274LMNA | |
| SCHEMBL11301090 | 0.68 | LMNA (0.53) | NISCHLMNARECQL | |
| SCHEMBL4383375 | 0.68 | NISCH (0.50) | NISCHLMNARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119948029-A | Fused tricyclic PARP1 inhibitor, preparation method and application thereof | 上海海和药物研究开发股份有限公司 | 2025-05-06 | — | — | CN | disclosed |