Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.42 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 2/20 | 0.40 |
| ▸ | RET | P07949 | 1/20 | 0.40 |
| ▸ | KIF5B | P33176 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9601982 | 0.81 | NQO2 (0.52) | PGK1SMN1; SMN2ALDH1A1PDE3BPDE3A | |
| SCHEMBL1289556 | 0.77 | KDM4E (0.47) | SMN1; SMN2ALDH1A1HTTKDM4EACHE | |
| SCHEMBL1291729 | 0.75 | PGK1 (0.68) | PGK1SMN1; SMN2ALDH1A1ENPP1KDM4E | |
| SCHEMBL31530749 | 0.75 | PGK1 (0.68) | PGK1SMN1; SMN2ALDH1A1ENPP1KDM4E | |
| SCHEMBL9593499 | 0.74 | PDE3B (0.46) | PGK1SMN1; SMN2ALDH1A1PDE3BPDE3A | |
| SCHEMBL9593886 | 0.74 | PDE3B (0.46) | PGK1SMN1; SMN2ALDH1A1PDE3BPDE3A | |
| SCHEMBL9594784 | 0.74 | PDE3B (0.46) | PGK1SMN1; SMN2ALDH1A1PDE3BPDE3A | |
| SCHEMBL31554433 | 0.73 | PDE3B (0.40) | SMN1; SMN2ALDH1A1PDE3BPDE3AHTT | |
| SCHEMBL294809 | 0.73 | SMN1; SMN2 (0.56) | PGK1SMN1; SMN2ALDH1A1PDE3BPDE3A | |
| SCHEMBL29532044 | 0.73 | SMN1; SMN2 (0.56) | PGK1SMN1; SMN2ALDH1A1PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025096463-A1 | PLK4 MODULATORS | VIBLIOME THERAPEUTICS, LLC (US) | 2025-05-08 | — | — | WO | disclosed |