Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 3/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.40 |
| ▸ | EGFR | P00533 | 5/20 | 0.37 |
| ▸ | KDR | P35968 | 6/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | WHR1 | P49842 | 2/20 | 0.34 |
| ▸ | RET | P07949 | 2/20 | 0.33 |
| ▸ | KIF5B | P33176 | 2/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.33 |
| ▸ | TUBB | P07437 | 1/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.33 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.33 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.33 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.33 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.33 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15834243 | 0.75 | PDE3B (0.35) | PDE3BPDE3AEGFRKDRKDM4E | |
| SCHEMBL20745790 | 0.75 | ACHE (0.52) | POLBSMN1; SMN2 | |
| SCHEMBL31554482 | 0.73 | PGK1 (0.47) | PDE3BPDE3AEGFRKDRKDM4E | |
| SCHEMBL15834270 | 0.71 | PDE3B (0.40) | PDE3BPDE3AKDM4EPOLBSMN1; SMN2 | |
| SCHEMBL30485653 | 0.71 | PTGS2 (0.34) | KDRSMN1; SMN2KMT2AALDH1A1HTT | |
| SCHEMBL22573256 | 0.71 | PTGS2 (0.34) | KDRSMN1; SMN2KMT2AALDH1A1HTT | |
| SCHEMBL5258067 | 0.71 | SRC (0.48) | EGFR | |
| SCHEMBL25267484 | 0.70 | CYP3A4 (0.53) | PDE3BPDE3AKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL3894223 | 0.70 | SRC (0.45) | EGFRKDR | |
| SCHEMBL16543572 | 0.69 | PDGFRB (0.48) | PDE3BPDE3ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025096463-A1 | PLK4 MODULATORS | VIBLIOME THERAPEUTICS, LLC (US) | 2025-05-08 | — | — | WO | disclosed |