Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.44 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25319004 | 1.00 | PTGS2 (0.44) | PTGS2DGAT1PDE3BPDE3ADRD2 | |
| SCHEMBL31097874 | 1.00 | PTGS2 (0.44) | PTGS2DGAT1PDE3BPDE3ADRD2 | |
| SCHEMBL15959129 | 0.86 | CYP2A6 (0.45) | PTGS2DGAT1TDO2PTGS1SLC22A12 | |
| SCHEMBL31351710 | 0.83 | FFAR4 (0.43) | PTGS2DGAT1DRD2DRD3PTGS1 | |
| SCHEMBL1805795 | 0.83 | CYP11B1 (0.48) | PTGS2PDE3BPDE3ADRD2DRD3 | |
| SCHEMBL12660790 | 0.82 | DRD2 (0.41) | PTGS2DRD2DRD3HSD11B1CA1 | |
| SCHEMBL1805846 | 0.81 | SMN1; SMN2 (0.44) | PTGS2DRD2DRD3KMT2APTGS1 | |
| SCHEMBL27881016 | 0.80 | SLC2A1 (0.47) | PTGS2PDE3BPDE3ADRD2DRD3 | |
| SCHEMBL752015 | 0.80 | CXCR2 (0.39) | PTGS2DRD2DRD3HSD11B1KMT2A | |
| SCHEMBL15613700 | 0.76 | PTGS2 (0.48) | PTGS2DRD2DRD3PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250122173-A1 | MODULATORS OF RHO-ASSOCIATED PROTEIN KINASE | REDX PHARMA LTD (GB) | 2025-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250122173-A1 | MODULATORS OF RHO-ASSOCIATED PROTEIN KINASE | ROCK1, ROCK2, RHOA | PTGS2 441/4885DGAT1 1559/4885PDE3B 345/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.