Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 2/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6357916 | 0.82 | CTRB1 (0.39) | CTRB1PLAUSIRT2 | |
| SCHEMBL9180411 | 0.81 | GAA (0.39) | CES2CES1 | |
| SCHEMBL6048200 | 0.81 | SIRT2 (0.45) | CTRB1PLAUSIRT2 | |
| SCHEMBL6261980 | 0.78 | MAPT (0.37) | — | |
| SCHEMBL31560348 | 0.77 | SLC6A2 (0.38) | CTRB1SIRT2 | |
| SCHEMBL657180 | 0.77 | SLC6A2 (0.38) | CTRB1SIRT2 | |
| SCHEMBL12370984 | 0.75 | GRM2 (0.30) | — | |
| SCHEMBL31462691 | 0.74 | TRPM5 (0.35) | CTRB1 | |
| SCHEMBL12370951 | 0.74 | — | — | |
| SCHEMBL7105128 | 0.73 | CTRB1 (0.39) | CTRB1PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025076088-A1 | LACTAMS FOR USE AS SARM1 INHIBITORS | GENENTECH, INC. (US) | 2025-04-10 | — | — | WO | disclosed |