Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 2/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31462691 | 0.87 | TRPM5 (0.35) | CTRB1MEN1KMT2ATP53 | |
| SCHEMBL6265155 | 0.83 | ALDH1A1 (0.40) | MEN1ALDH1A1KMT2AMAOB | |
| SCHEMBL31560367 | 0.82 | CTRB1 (0.38) | CTRB1PLAUSIRT2 | |
| SCHEMBL5856736 | 0.81 | KDM4E (0.47) | CTRB1CYP19A1HCAR2KDM4EMEN1 | |
| SCHEMBL658679 | 0.79 | MAP1LC3B (0.49) | CTRB1PLAUALDH1A1KMT2ASIRT2 | |
| SCHEMBL7105128 | 0.75 | CTRB1 (0.39) | CTRB1PLAUMEN1ALDH1A1KMT2A | |
| SCHEMBL10017608 | 0.75 | CTRB1 (0.53) | CTRB1PLAUALDH1A1SMN1; SMN2MAP1LC3B | |
| SCHEMBL6048200 | 0.75 | SIRT2 (0.45) | CTRB1PLAUHCAR2SIRT2 | |
| SCHEMBL12371035 | 0.74 | NPY5R (0.33) | CYP19A1GRM2 | |
| SCHEMBL6261980 | 0.72 | MAPT (0.37) | CYP19A1MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025076088-A1 | LACTAMS FOR USE AS SARM1 INHIBITORS | GENENTECH, INC. (US) | 2025-04-10 | — | — | WO | disclosed |
| US-20050043344-A1 | Heteroarylalkanoic acids as integrin receptor antagonists derivatives | PHARMACIA CORPORATION | 2005-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050043344-A1 | Heteroarylalkanoic acids as integrin receptor antagonists derivatives | ITGA5, ITGAV, ITGA6 | CTRB1 3499/4885CYP19A1 4762/4885PLAU 1114/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.