Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | EP300 | Q09472 | 5/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 5/20 | 0.41 |
| ▸ | IDO1 | P14902 | 3/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31560715 | 0.96 | HSD11B1 (0.40) | TRPV1EP300CREBBPIDO1KCNH2 | |
| SCHEMBL31560533 | 0.86 | HDAC4 (0.56) | HDAC4ALDH1A1HSD11B1 | |
| SCHEMBL31560530 | 0.86 | ALDH1A1 (0.43) | TRPV1IDO1KCNH2HDAC4ALDH1A1 | |
| SCHEMBL31560575 | 0.85 | HDAC4 (0.52) | HDAC4ALDH1A1HSD11B1 | |
| SCHEMBL31560526 | 0.85 | HDAC4 (0.50) | HDAC4ALDH1A1FTOHSD11B1 | |
| SCHEMBL31560520 | 0.82 | HDAC4 (0.54) | HDAC4ALDH1A1HSD11B1 | |
| SCHEMBL31560499 | 0.82 | ALDH1A1 (0.44) | TRPV1KCNH2HDAC4ALDH1A1SLC6A4 | |
| SCHEMBL31560707 | 0.82 | HSD11B1 (0.52) | HDAC4ALDH1A1HSD11B1 | |
| SCHEMBL31560749 | 0.81 | HSD11B1 (0.50) | HDAC4ALDH1A1HSD11B1 | |
| SCHEMBL31560772 | 0.80 | HDAC4 (0.53) | HDAC4ALDH1A1FTOSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025074305-A1 | N-(1-(AMINOMETHYL)CYCLOPROPYL)(ARYL OR HETEROARYL) CARBOXAMIDE DERIVATIVES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2025-04-10 | — | — | WO | claimed |
| WO-2025074305-A1 | N-(1-(AMINOMETHYL)CYCLOPROPYL)(ARYL OR HETEROARYL) CARBOXAMIDE DERIVATIVES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2025-04-10 | — | — | WO | disclosed |