Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31560526 | 0.96 | HDAC4 (0.50) | HSD11B1HDAC4SMN1; SMN2HTTLMNA | |
| SCHEMBL31560652 | 0.91 | ELOVL1 (0.44) | HSD11B1HDAC4SMN1; SMN2HTTLMNA | |
| SCHEMBL31560634 | 0.89 | HDAC4 (0.40) | HSD11B1HDAC4SMN1; SMN2HTTLMNA | |
| SCHEMBL31560539 | 0.86 | HSD11B1 (0.47) | HSD11B1HDAC4SMN1; SMN2LMNAELOVL1 | |
| SCHEMBL31560707 | 0.86 | HSD11B1 (0.52) | HSD11B1HDAC4SMN1; SMN2HTTLMNA | |
| SCHEMBL31560677 | 0.86 | OPRM1 (0.40) | HSD11B1HDAC4LMNANPSR1MEN1 | |
| SCHEMBL31560520 | 0.85 | HDAC4 (0.54) | HSD11B1HDAC4NPSR1MEN1KMT2A | |
| SCHEMBL31560499 | 0.85 | ALDH1A1 (0.44) | HDAC4SMN1; SMN2LMNANPSR1MEN1 | |
| SCHEMBL31560715 | 0.85 | HSD11B1 (0.40) | HSD11B1HDAC4MEN1KMT2AALDH1A1 | |
| SCHEMBL31560538 | 0.83 | MAPT (0.42) | HSD11B1HDAC4SMN1; SMN2LMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025074305-A1 | N-(1-(AMINOMETHYL)CYCLOPROPYL)(ARYL OR HETEROARYL) CARBOXAMIDE DERIVATIVES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2025-04-10 | — | — | WO | claimed |
| WO-2025074305-A1 | N-(1-(AMINOMETHYL)CYCLOPROPYL)(ARYL OR HETEROARYL) CARBOXAMIDE DERIVATIVES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2025-04-10 | — | — | WO | disclosed |