SCHEMBL3156325

SCHEMBL3156325

CN1CCC=C(c2ccc(Br)cc2)C1

nearest known ligand 0.55

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 1/20 0.55
CHRNA4 P43681 1/20 0.55
LSS P48449 2/20 0.54
CHRM1 P11229 2/20 0.46
CHRM2 P08172 3/20 0.44
CHRM3 P20309 3/20 0.44
CHRNB4 P30926 1/20 0.43
CHRNA3 P32297 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12950949 0.83 CHRNB2 (0.57) CHRNB2CHRNA4LSSCHRM1CHRM2
SCHEMBL10644523 0.81 CHRNB4 (0.60) CHRNB2CHRNA4LSSCHRM1CHRM2
Hydrochloric Acid SCHEMBL10760183 0.79 CHRNB4 (0.58) CHRNB2CHRNA4LSSCHRM1CHRM2
SCHEMBL12925945 0.79 CHRNB2 (0.56) CHRNB2CHRNA4LSSCHRM1CHRM2
SCHEMBL1673515 0.77 LSS (0.61) CHRNB2CHRNA4LSSCHRM1CHRM2
SCHEMBL997728 0.75 CYP2D6 (0.45) CHRNB2CHRNA4LSSCHRM2CHRM3
SCHEMBL999807 0.75 KCNH2 (0.39) CHRNB2CHRNA4LSSCHRM1CHRM2
SCHEMBL578138 0.72 QDPR (0.68)
SCHEMBL25916643 0.72 LPL (0.47) CHRNB2CHRNA4LSSCHRM1CHRM2
SCHEMBL1673767 0.70 LSS (0.52) CHRNB2CHRNA4LSSCHRM1CHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2166584-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ORGANIC ELECTROLUMINESCENCE ELEMENT PREPARED BY USING THE MATERIAL Idemitsu Kosan Co., Ltd. (JP) 2010-03-24 EP disclosed