Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | HPGD | P15428 | 5/20 | 0.47 |
| ▸ | CASP1 | P29466 | 3/20 | 0.43 |
| ▸ | CSNK1D | P48730 | 3/20 | 0.43 |
| ▸ | CASP7 | P55210 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KLK7 | P49862 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31563757 | 1.00 | KDM4E (0.51) | KDM4EHSD17B10SMN1; SMN2GAATSHR | |
| SCHEMBL29046221 | 0.84 | KDM4E (0.62) | KDM4EHSD17B10SMN1; SMN2GAATSHR | |
| SCHEMBL17781088 | 0.81 | KDM4E (0.54) | KDM4EHSD17B10SMN1; SMN2GAATSHR | |
| SCHEMBL22105269 | 0.79 | KDM4E (0.55) | KDM4EHSD17B10SMN1; SMN2GAATSHR | |
| SCHEMBL21961705 | 0.78 | KDM4E (0.51) | KDM4EHSD17B10SMN1; SMN2GAATSHR | |
| SCHEMBL19680290 | 0.76 | KDM4E (0.56) | KDM4EHSD17B10SMN1; SMN2GAATSHR | |
| SCHEMBL24496898 | 0.75 | ADORA3 (0.47) | KDM4EHSD17B10SMN1; SMN2GAATSHR | |
| SCHEMBL5598086 | 0.75 | KDM4E (0.61) | KDM4EHSD17B10SMN1; SMN2GAATSHR | |
| SCHEMBL5598029 | 0.75 | SMN1; SMN2 (0.55) | KDM4EHSD17B10SMN1; SMN2GAATSHR | |
| SCHEMBL25118087 | 0.74 | ALDH1A1 (0.64) | KDM4EHSD17B10SMN1; SMN2GAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116265467-B | Intermediate for synthesizing TYK2 inhibitor, and preparation method and application thereof | 成都科岭源医药技术有限公司 | 2025-04-18 | — | — | CN | disclosed |