Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.32 |
| ▸ | ASGR1 | P07306 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.32 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 2/20 | 0.31 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.31 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.31 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31563996 | 1.00 | HSD11B1 (0.33) | HSD11B1KDM4DASGR1DRD2DRD4 | |
| SCHEMBL31563889 | 0.90 | NPC1 (0.35) | HSD11B1KDM4DDRD2DRD4DRD3 | |
| SCHEMBL31564374 | 0.86 | HSD11B1 (0.34) | HSD11B1KDM4DASGR1DRD2DRD4 | |
| SCHEMBL31564466 | 0.86 | ADORA2A (0.35) | HSD11B1KDM4DASGR1DRD2DRD4 | |
| SCHEMBL31563832 | 0.85 | HSD11B1 (0.33) | HSD11B1KDM4DASGR1DRD2NPY5R | |
| SCHEMBL31564424 | 0.85 | PNMT (0.35) | HSD11B1KDM4DASGR1DRD2NPY5R | |
| SCHEMBL31564057 | 0.84 | KCNQ2 (0.33) | HSD11B1KDM4DASGR1DRD2NPY5R | |
| SCHEMBL31563886 | 0.84 | ALDH1A1 (0.43) | HSD11B1KDM4DASGR1NPY5R | |
| SCHEMBL31564435 | 0.84 | KCNQ2 (0.33) | HSD11B1KDM4DASGR1DRD2NPY5R | |
| SCHEMBL31563985 | 0.82 | PNMT (0.39) | HSD11B1KDM4DASGR1NPY5RKCNQ2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025097104-A1 | THIENYL COMPOUNDS FOR THE TREATMENT OF A CENTRAL NERVOUS SYSTEM DISEASE OR DISORDER | PGI DRUG DISCOVERY LLC (US) | 2025-05-08 | — | — | WO | disclosed |