SCHEMBL31565579

SCHEMBL31565579

Cn1cc(-c2nn(C3CCN(C(=O)OC(C)(C)C)CC3)c3ccc(Br)cc23)cn1

nearest known ligand 0.48

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ GPR119 Q8TDV5 4/20 0.48
▸ BTK Q06187 1/20 0.43
▸ USP30 Q70CQ3 2/20 0.43
▸ RET P07949 3/20 0.42
▸ AXL P30530 6/20 0.41
▸ MERTK Q12866 5/20 0.41
▸ TYRO3 Q06418 4/20 0.41
▸ LRRK2 Q5S007 1/20 0.40
▸ NR3C1 P04150 1/20 0.40
▸ PIK3CA P42336 1/20 0.39
▸ MTOR P42345 1/20 0.39
▸ PIK3CG P48736 1/20 0.39
▸ ATR Q13535 1/20 0.39
▸ AURKB Q96GD4 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24148625 0.82 AXL (0.46) GPR119USP30RETAXLLRRK2
SCHEMBL8820197 0.80 GPR119 (0.46) GPR119USP30NR3C1
SCHEMBL8818888 0.79 GPR119 (0.44) GPR119USP30
SCHEMBL7350588 0.79 GPR119 (0.49) GPR119USP30NR3C1PIK3CAPIK3CG
SCHEMBL7344659 0.79 GPR119 (0.53) GPR119USP30NR3C1
SCHEMBL31583380 0.79 GPR119 (0.44) GPR119USP30NR3C1
SCHEMBL15656816 0.78 GPR119 (0.44) GPR119BTKUSP30NR3C1
SCHEMBL31565532 0.77 CREBBP (0.67) —
SCHEMBL10060450 0.77 GPR119 (0.68) GPR119USP30NR3C1PIK3CAMTOR
SCHEMBL29507014 0.77 GPR119 (0.68) GPR119USP30NR3C1PIK3CAMTOR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250129070-A1 BIFUNCTIONAL ANDROGEN RECEPTOR COMPOUNDS KOLM THERAPEUTICS INC. 2025-04-24 — — US disclosed
WO-2025081082-A1 BIFUNCTIONAL ANDROGEN RECEPTOR COMPOUNDS KOLM THERAPEUTICS INC. (US) 2025-04-17 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250129070-A1 BIFUNCTIONAL ANDROGEN RECEPTOR COMPOUNDS AR, SHBG, FSHR GPR119 245/4885BTK 1838/4885USP30 1156/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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