Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 7/20 | 0.35 |
| ▸ | CHUK | O15111 | 7/20 | 0.35 |
| ▸ | MAT2A | P31153 | 1/20 | 0.35 |
| ▸ | USP1 | O94782 | 5/20 | 0.33 |
| ▸ | WDR48 | Q8TAF3 | 2/20 | 0.33 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.32 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 2/20 | 0.31 |
| ▸ | BTK | Q06187 | 2/20 | 0.31 |
| ▸ | ITK | Q08881 | 2/20 | 0.31 |
| ▸ | IKBKE | Q14164 | 2/20 | 0.31 |
| ▸ | PLK1 | P53350 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31566299 | 0.82 | DYRK1A (0.37) | USP1WDR48TRPC5PIP4K2CCTSL | |
| SCHEMBL31566326 | 0.82 | LMNA (0.38) | USP1TRPC5PIP4K2CTRPA1DPP4 | |
| SCHEMBL31566327 | 0.80 | USP1 (0.34) | USP1TRPC5PIP4K2CTRPA1DPP4 | |
| SCHEMBL31566328 | 0.77 | TSHR (0.41) | USP1TRPC5PIP4K2CDPP4GRM5 | |
| SCHEMBL31566330 | 0.75 | USP1 (0.34) | USP1WDR48DPP4KMT2AGRM5 | |
| SCHEMBL31566332 | 0.73 | MEN1 (0.34) | USP1MEN1KMT2A | |
| SCHEMBL31566321 | 0.71 | CDK1 (0.48) | USP1CDK2 | |
| SCHEMBL31566297 | 0.71 | BRD4 (0.36) | USP1TRPC5 | |
| SCHEMBL31566301 | 0.69 | ATR (0.36) | IKBKBCHUKUSP1WDR48PIP4K2C | |
| SCHEMBL18409182 | 0.68 | CDK1 (0.42) | IKBKBCHUKCDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025096505-A1 | UBIQUITIN SPECIFIC PROCESSING PROTEASE 1 (USP1) COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-05-08 | — | — | WO | disclosed |