Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | USP1 | O94782 | 5/20 | 0.34 |
| ▸ | NAT1 | P18440 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.31 |
| ▸ | C1R | P00736 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31566322 | 0.92 | PSEN1 (0.34) | USP1NPSR1CA12CA1CA2 | |
| SCHEMBL31566320 | 0.92 | PSEN1 (0.34) | USP1NPSR1CA12CA1CA2 | |
| SCHEMBL31566318 | 0.84 | USP1 (0.44) | USP1 | |
| SCHEMBL31566297 | 0.76 | BRD4 (0.36) | USP1 | |
| SCHEMBL31566299 | 0.75 | DYRK1A (0.37) | USP1CA12CA1CA2CA9 | |
| SCHEMBL31566326 | 0.75 | LMNA (0.38) | MEN1KMT2AUSP1 | |
| SCHEMBL31566306 | 0.73 | IKBKB (0.35) | MEN1KMT2AUSP1 | |
| SCHEMBL31566327 | 0.72 | USP1 (0.34) | USP1 | |
| SCHEMBL31566330 | 0.70 | USP1 (0.34) | KMT2AUSP1 | |
| SCHEMBL31566328 | 0.69 | TSHR (0.41) | USP1ALDH1A1TSHRCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025096505-A1 | UBIQUITIN SPECIFIC PROCESSING PROTEASE 1 (USP1) COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-05-08 | — | — | WO | disclosed |