SCHEMBL31574401

SCHEMBL31574401

Cn1cc(Cl)c(O)cc1=O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BAZ2B Q9UIF8 1/20 0.45
BAZ2A Q9UIF9 1/20 0.45
MAP2K2 P36507 1/20 0.38
MAP2K1 Q02750 1/20 0.38
ADRA1A P35348 1/20 0.38
HSD17B10 Q99714 3/20 0.37
TSHR P16473 2/20 0.37
HPGD P15428 2/20 0.37
ATAD2 Q6PL18 1/20 0.35
HSP90AA1 P07900 2/20 0.35
APP P05067 1/20 0.34
ALDH1A1 P00352 3/20 0.33
CYP3A4 P08684 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
MCL1 Q07820 1/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
KDM4E B2RXH2 1/20 0.32
MAPT P10636 1/20 0.32
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12767251 0.76 BAZ2B (0.39) BAZ2BBAZ2AMAP2K2MAP2K1HSD17B10
SCHEMBL21904988 0.74 ATAD2 (0.35) BAZ2BBAZ2AMAP2K2MAP2K1HSD17B10
SCHEMBL20532579 0.74 BAZ2B (0.41) BAZ2BBAZ2AMAP2K2MAP2K1ATAD2
SCHEMBL12261136 0.74 ATAD2 (0.35) BAZ2BBAZ2AMAP2K2MAP2K1HSD17B10
SCHEMBL9694570 0.71 ADRA1A (0.32) BAZ2BBAZ2AADRA1AHSD17B10TSHR
SCHEMBL22448626 0.71 LMNA (0.39) ADRA1AHPGDATAD2HSP90AA1APP
SCHEMBL1526095 0.71 MAP2K2 (0.44) BAZ2BBAZ2AMAP2K2MAP2K1HSD17B10
SCHEMBL15551166 0.71 MAPT (0.47) BAZ2BBAZ2ATSHRHSP90AA1ALDH1A1
SCHEMBL27304728 0.71 BAZ2B (0.39) BAZ2BBAZ2AMAP2K2MAP2K1TSHR
SCHEMBL9670234 0.70 BAZ2B (0.33) BAZ2BBAZ2AADRA1AHSD17B10TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119985732-A Detection analysis method and application of pyridine compounds in 2-pyridones 四川科伦药物研究院有限公司 2025-05-13 CN claimed
CN-119985732-A Detection analysis method and application of pyridine compounds in 2-pyridones 四川科伦药物研究院有限公司 2025-05-13 CN disclosed