Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHMT2 | P34897 | 5/20 | 0.46 |
| ▸ | SHMT1 | P34896 | 4/20 | 0.46 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | PPID | Q08752 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31578923 | 0.89 | SHMT2 (0.55) | SHMT2SHMT1GAALTC4SPOLB | |
| SCHEMBL31578774 | 0.89 | KMT2A (0.47) | GAALTC4SKMT2AHTTPOLB | |
| SCHEMBL31578658 | 0.86 | SHMT2 (0.62) | SHMT2SHMT1DGAT2GAALMNA | |
| SCHEMBL31578783 | 0.82 | GAA (0.51) | SHMT2SHMT1GAAKMT2AHTT | |
| SCHEMBL31578632 | 0.80 | SHMT2 (0.52) | SHMT2SHMT1GAALTC4SKMT2A | |
| SCHEMBL31578724 | 0.77 | SHMT2 (0.53) | SHMT2SHMT1GAAKMT2ALMNA | |
| SCHEMBL31578811 | 0.77 | LTC4S (0.56) | GAALTC4SKMT2APOLBLMNA | |
| SCHEMBL31578742 | 0.74 | SMN1; SMN2 (0.44) | SHMT2SHMT1DGAT2GAAPOLB | |
| SCHEMBL31578814 | 0.74 | SHMT2 (0.75) | SHMT2SHMT1GAALMNAALDH1A1 | |
| SCHEMBL16269205 | 0.73 | HDAC6 (0.51) | DGAT2GAAHTTPPIDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250163075-A1 | HETEROBIFUNCTIONAL TARGETED PROTEIN DEGRADERS | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2025-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250163075-A1 | HETEROBIFUNCTIONAL TARGETED PROTEIN DEGRADERS | KLHDC2, KLHL6, KLHL20 | SHMT2 1737/4885SHMT1 1027/4885DGAT2 3487/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.