Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31578791 | 0.90 | MAPK1 (0.45) | MAPTALDH1A1KMT2AMEN1LTC4S | |
| SCHEMBL31578905 | 0.84 | MAPT (0.40) | MAPTALDH1A1KMT2AMEN1LTC4S | |
| Hydrochloric Acid SCHEMBL31578794 | 0.83 | MAPT (0.39) | MAPTALDH1A1KMT2AMEN1LTC4S | |
| SCHEMBL31578699 | 0.83 | ALDH1A1 (0.48) | MAPTALDH1A1KMT2AMEN1LTC4S | |
| SCHEMBL31578742 | 0.81 | SMN1; SMN2 (0.44) | MAPTALDH1A1GAAKDM4EMAPK1 | |
| SCHEMBL31578678 | 0.81 | ALDH1A1 (0.53) | MAPTALDH1A1KMT2AMEN1TDP1 | |
| SCHEMBL31578759 | 0.81 | ACKR3 (0.38) | MAPTALDH1A1KMT2AMEN1LTC4S | |
| SCHEMBL31578793 | 0.80 | ACKR3 (0.48) | — | |
| SCHEMBL31578670 | 0.79 | ALDH1A1 (0.60) | MAPTALDH1A1KMT2AMEN1GAA | |
| SCHEMBL11164179 | 0.76 | MEN1 (0.60) | MAPTALDH1A1KMT2AMEN1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250163075-A1 | HETEROBIFUNCTIONAL TARGETED PROTEIN DEGRADERS | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2025-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250163075-A1 | HETEROBIFUNCTIONAL TARGETED PROTEIN DEGRADERS | KLHDC2, KLHL6, KLHL20 | MAPT 2043/4885ALDH1A1 2481/4885KMT2A 253/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.