Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.36 |
| ▸ | PTPRB | P23467 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.36 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31578793 | 0.92 | ACKR3 (0.48) | ACKR3 | |
| SCHEMBL31578905 | 0.86 | MAPT (0.40) | MAPTALDH1A1MEN1KMT2ATRPV4 | |
| Hydrochloric Acid SCHEMBL31578794 | 0.86 | MAPT (0.39) | MAPTALDH1A1MEN1KMT2ATRPV4 | |
| SCHEMBL31578816 | 0.85 | ACKR3 (0.47) | ACKR3 | |
| SCHEMBL31578664 | 0.82 | ACKR3 (0.53) | ACKR3ALDH1A1 | |
| SCHEMBL31578820 | 0.81 | MAPT (0.44) | MAPTALDH1A1MEN1KMT2ALTC4S | |
| SCHEMBL31578791 | 0.81 | MAPK1 (0.45) | MAPTALDH1A1MEN1KMT2ALTC4S | |
| SCHEMBL31578870 | 0.80 | FGFR1 (0.37) | MAPTALDH1A1MEN1KMT2ALTC4S | |
| SCHEMBL31578853 | 0.77 | ACKR3 (0.48) | ACKR3MAPTALDH1A1 | |
| SCHEMBL31578699 | 0.74 | ALDH1A1 (0.48) | MAPTALDH1A1MEN1KMT2ALTC4S |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250163075-A1 | HETEROBIFUNCTIONAL TARGETED PROTEIN DEGRADERS | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2025-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250163075-A1 | HETEROBIFUNCTIONAL TARGETED PROTEIN DEGRADERS | KLHDC2, KLHL6, KLHL20 | ACKR3 3274/4885MAPT 2043/4885ALDH1A1 2481/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.