SCHEMBL31579010

SCHEMBL31579010

Cc1c(Br)ccc2c1cc(C#N)n2S(=O)(=O)c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ PTGDR Q13258 1/20 0.39
▸ PTGDR2 Q9Y5Y4 1/20 0.39
▸ SRC P12931 2/20 0.39
▸ HTR6 P50406 9/20 0.38
▸ BRD4 O60885 1/20 0.38
▸ ACLY P53396 2/20 0.37
▸ L3MBTL1 Q9Y468 1/20 0.35
▸ LMNA P02545 1/20 0.34
▸ AGTR1 P30556 1/20 0.34
▸ PPARG P37231 1/20 0.34
▸ PPARA Q07869 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30405736 0.84 HTR6 (0.39) PTGDRPTGDR2SRCHTR6L3MBTL1
SCHEMBL25424320 0.84 HTR6 (0.39) PTGDRPTGDR2SRCHTR6L3MBTL1
SCHEMBL31579098 0.83 KDM4E (0.38) PTGDRPTGDR2SRCHTR6BRD4
SCHEMBL31578890 0.82 PTGDR (0.37) PTGDRPTGDR2SRCHTR6BRD4
SCHEMBL25423168 0.81 SRC (0.41) PTGDRPTGDR2SRCHTR6BRD4
SCHEMBL25420154 0.75 MTNR1B (0.54) SRCHTR6ACLY
SCHEMBL25421448 0.73 CA12 (0.51) SRCHTR6LMNAPPARGPPARA
SCHEMBL31023100 0.72 AR (0.42) SRCL3MBTL1LMNA
SCHEMBL24015624 0.72 HTR6 (0.52) PTGDRPTGDR2SRCHTR6BRD4
SCHEMBL597369 0.69 HTR6 (0.46) PTGDRPTGDR2SRCHTR6BRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260022120-A1 Inhibitors of MENIN-MLL Interaction BALA THERAPEUTICS INC (US) 2026-01-22 — — US disclosed
US-20250163061-A1 INHIBITORS OF MENIN-MLL INTERACTION BALA THERAPEUTICS, INC. 2025-05-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250163061-A1 INHIBITORS OF MENIN-MLL INTERACTION MLLT1, MEN1, BMI1 PTGDR 4314/4885PTGDR2 4063/4885SRC 2212/4885
US-20260022120-A1 Inhibitors of MENIN-MLL Interaction MEN1, MLLT1, MLLT3 PTGDR 4531/4885PTGDR2 4556/4885SRC 391/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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