SCHEMBL25423168

SCHEMBL25423168

Cc1cccc2c1cc(C#N)n2S(=O)(=O)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SRC P12931 1/20 0.41
▸ BRD4 O60885 1/20 0.40
▸ CNR2 P34972 1/20 0.39
▸ TDP1 Q9NUW8 1/20 0.39
▸ PTGDR Q13258 1/20 0.39
▸ PTGDR2 Q9Y5Y4 1/20 0.39
▸ HTR6 P50406 10/20 0.38
▸ AGTR1 P30556 2/20 0.38
▸ HTR1A P08908 1/20 0.38
▸ DRD2 P14416 1/20 0.38
▸ HTR1D P28221 1/20 0.38
▸ HTR1B P28222 1/20 0.38
▸ HTR1F P30939 1/20 0.38
▸ HTR7 P34969 1/20 0.38
▸ DRD3 P35462 1/20 0.38
▸ MTNR1B P49286 1/20 0.37
▸ CXCL8 P10145 1/20 0.37
▸ NOD1 Q9Y239 1/20 0.37
▸ PSEN1 P49768 1/20 0.37
▸ PSEN2 P49810 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20762057 0.84 BRD4 (0.49) SRCBRD4TDP1PTGDRPTGDR2
SCHEMBL25420154 0.83 MTNR1B (0.54) SRCHTR6MTNR1B
SCHEMBL31579010 0.81 PTGDR (0.39) SRCBRD4PTGDRPTGDR2HTR6
SCHEMBL31579098 0.79 KDM4E (0.38) SRCBRD4PTGDRPTGDR2HTR6
SCHEMBL25421448 0.79 CA12 (0.51) SRCCNR2HTR6CXCL8NOD1
SCHEMBL31578890 0.78 PTGDR (0.37) SRCBRD4PTGDRPTGDR2HTR6
SCHEMBL10003024 0.77 HTR6 (0.47) SRCCNR2PTGDRPTGDR2HTR6
SCHEMBL20742950 0.77 CCR2 (0.51) SRCPTGDRPTGDR2HTR6AGTR1
SCHEMBL31578980 0.77 CCR2 (0.51) SRCPTGDRPTGDR2HTR6AGTR1
SCHEMBL25424320 0.75 HTR6 (0.39) SRCPTGDRPTGDR2HTR6MTNR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260022120-A1 Inhibitors of MENIN-MLL Interaction BALA THERAPEUTICS INC (US) 2026-01-22 — — US disclosed
US-20250163061-A1 INHIBITORS OF MENIN-MLL INTERACTION BALA THERAPEUTICS, INC. 2025-05-22 — — US disclosed
EP-4444300-A2 INHIBITORS OF MENIN-MLL INTERACTION Bala Therapeutics, Inc. (US) 2024-10-16 — — EP disclosed
WO-2023107696-A2 INHIBITORS OF MENIN-MLL INTERACTION BALA THERAPEUTICS, INC. (US) 2023-06-15 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250163061-A1 INHIBITORS OF MENIN-MLL INTERACTION MLLT1, MEN1, BMI1 SRC 2212/4885BRD4 81/4885CNR2 4294/4885
US-20260022120-A1 Inhibitors of MENIN-MLL Interaction MEN1, MLLT1, MLLT3 SRC 391/4885BRD4 291/4885CNR2 3477/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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