Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.30 |
| ▸ | EDNRA | P25101 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31582842 | 0.87 | KDM4E (0.36) | ESR1EDNRAPOLB | |
| SCHEMBL31582995 | 0.76 | MTNR1A (0.36) | ESR1POLB | |
| SCHEMBL31582981 | 0.76 | LMNA (0.36) | AAK1 | |
| SCHEMBL31582650 | 0.75 | SLC16A3 (0.34) | — | |
| SCHEMBL31582655 | 0.75 | LMNA (0.33) | — | |
| SCHEMBL31583219 | 0.74 | LMNA (0.35) | POLB | |
| SCHEMBL31583107 | 0.74 | SMN1; SMN2 (0.31) | — | |
| SCHEMBL31582472 | 0.71 | JAK2 (0.34) | EDNRA | |
| SCHEMBL31583384 | 0.69 | ESR1 (0.38) | ESR1POLB | |
| SCHEMBL31582797 | 0.68 | CYP2A6 (0.33) | AAK1EDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025106644-A1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF ALPHA-V BETA-1 INTEGRIN | MORPHIC THERAPEUTIC, INC. (US) | 2025-05-22 | — | — | WO | disclosed |