Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31583078 | 0.87 | L3MBTL1 (0.38) | MTNR1AMTNR1BL3MBTL1POLBESR1 | |
| SCHEMBL31582836 | 0.76 | ESR1 (0.34) | POLBESR1 | |
| SCHEMBL31582832 | 0.75 | SMN1; SMN2 (0.36) | MTNR1AMTNR1BL3MBTL1RORCSIRT5 | |
| SCHEMBL31583259 | 0.75 | L3MBTL1 (0.36) | MTNR1AMTNR1BL3MBTL1RORCSIRT5 | |
| SCHEMBL31583192 | 0.73 | L3MBTL1 (0.38) | MTNR1AMTNR1BL3MBTL1POLBSIRT5 | |
| SCHEMBL31583096 | 0.73 | L3MBTL1 (0.40) | MTNR1AMTNR1BL3MBTL1SIRT5ACHE | |
| SCHEMBL31583076 | 0.73 | L3MBTL1 (0.38) | MTNR1AMTNR1BL3MBTL1POLBRORC | |
| SCHEMBL31582800 | 0.70 | L3MBTL1 (0.35) | MTNR1AMTNR1BL3MBTL1RORCACHE | |
| SCHEMBL9863289 | 0.69 | MTNR1A (0.52) | MTNR1AMTNR1BL3MBTL1RORCSIRT5 | |
| SCHEMBL2914936 | 0.69 | SIRT5 (0.59) | L3MBTL1SIRT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025106644-A1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF ALPHA-V BETA-1 INTEGRIN | MORPHIC THERAPEUTIC, INC. (US) | 2025-05-22 | — | — | WO | disclosed |