SCHEMBL31583592

SCHEMBL31583592

CC(C)(C)OC(=O)N1CC2(C1)CN(c1ccc(N3CCC(=O)NC3=O)c(F)c1)C2

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ DDB1 Q16531 4/20 0.41
▸ CRBN Q96SW2 4/20 0.41
▸ MMP2 P08253 1/20 0.40
▸ MMP13 P45452 1/20 0.40
▸ MMP14 P50281 1/20 0.40
▸ ADAMTS5 Q9UNA0 1/20 0.40
▸ PARP1 P09874 5/20 0.40
▸ HRH3 Q9Y5N1 4/20 0.39
▸ EGLN2 Q96KS0 1/20 0.38
▸ PDK2 Q15119 1/20 0.38
▸ GPR119 Q8TDV5 2/20 0.37
▸ TNKS O95271 2/20 0.36
▸ TNKS2 Q9H2K2 2/20 0.36
▸ USP30 Q70CQ3 1/20 0.36
▸ HDAC1 Q13547 1/20 0.36
▸ HDAC2 Q92769 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30703627 0.84 DDB1 (0.48) DDB1CRBNMMP2MMP13MMP14
SCHEMBL31630927 0.83 DDB1 (0.49) DDB1CRBNMMP2MMP13MMP14
SCHEMBL31583271 0.83 HRH3 (0.49) DDB1CRBNPARP1HRH3GPR119
SCHEMBL31583606 0.81 ADAMTS5 (0.50) DDB1CRBNMMP2MMP13MMP14
SCHEMBL30915074 0.80 DDB1 (0.56) DDB1CRBNPARP1EGLN2GPR119
SCHEMBL30768730 0.79 CYP11B2 (0.46) DDB1CRBNGPR119USP30HDAC1
SCHEMBL30643667 0.79 DDB1 (0.49) DDB1CRBNPDK2GPR119
SCHEMBL25197198 0.79 HDAC2 (0.46) MMP2MMP13MMP14ADAMTS5PARP1
SCHEMBL30952388 0.78 DDB1 (0.50) DDB1CRBNPDK2GPR119
SCHEMBL31306782 0.78 CYP3A4 (0.48) DDB1CRBNGPR119HDAC1HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025106910-A1 DEGRADER MOLECULES TARGETING ANDROGEN RECEPTOR FLARE THERAPEUTICS INC. (US) 2025-05-22 — — WO disclosed
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