Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 2/20 | 0.34 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.34 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5299145 | 0.84 | TSHR (0.49) | CHRNA7TSHRCHEK1CHEK2NPC1 | |
| SCHEMBL1712176 | 0.79 | CHRNA7 (0.45) | CHRNA7TSHRNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL103632 | 0.77 | CHRNA7 (0.47) | CHRNA7TSHRNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29747107 | 0.74 | CHEK2 (0.42) | CHRNA7TSHRCHEK2NPC1RAB9A | |
| SCHEMBL5917985 | 0.73 | KDM4E (0.51) | CHRNA7NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL18443469 | 0.70 | BACE1 (0.39) | CHRNA7TSHRNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL20270971 | 0.70 | BACE1 (0.39) | CHRNA7TSHRNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5265516 | 0.70 | GABRA1 (0.48) | TSHRNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL2507415 | 0.69 | CHRNA7 (0.41) | CHRNA7TSHRNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6389963 | 0.68 | ALDH1A1 (0.47) | CHRNA7NPC1RAB9ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025106949-A1 | WRN INHIBITORS | RADD PHARMACEUTICALS, INC. (US) | 2025-05-22 | — | — | WO | disclosed |