Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.45 |
| ▸ | PTGER1 | P34995 | 4/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.45 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.45 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20742381 | 0.84 | MTNR1B (0.42) | MTNR1AMTNR1BPTGER1CYP2C9CYP1A2 | |
| SCHEMBL20742383 | 0.84 | MTNR1B (0.42) | MTNR1AMTNR1BPTGER1CYP2C9CYP1A2 | |
| SCHEMBL31588132 | 0.84 | MTNR1B (0.42) | MTNR1AMTNR1BPTGER1CYP2C9CYP1A2 | |
| SCHEMBL9889103 | 0.81 | PTGER1 (0.50) | MTNR1AMTNR1BPTGER1PTGER4PTGER3 | |
| SCHEMBL20742626 | 0.81 | MTNR1A (0.41) | MTNR1AMTNR1BPTGER1CYP2C9CYP1A2 | |
| SCHEMBL20742625 | 0.81 | MTNR1A (0.41) | MTNR1AMTNR1BPTGER1CYP2C9CYP1A2 | |
| SCHEMBL29372330 | 0.80 | CA12 (0.39) | MTNR1AMTNR1BCYP2C9CYP1A2ALDH1A1 | |
| SCHEMBL9889129 | 0.80 | PTGER1 (0.49) | MTNR1AMTNR1BPTGER1PTGER4PTGER3 | |
| SCHEMBL31587683 | 0.79 | CA12 (0.39) | MTNR1AMTNR1BPOLB | |
| SCHEMBL3916435 | 0.79 | LTA4H (0.39) | LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025106634-A1 | MCL-1 INHIBITOR COMPOUNDS AND USE IN ANTIBODY DRUG CONJUGATES | GENENTECH, INC. (US) | 2025-05-22 | — | — | WO | disclosed |