Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 11/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | CASR | P41180 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29379232 | 0.78 | RXRA (0.42) | NOTUM | |
| SCHEMBL29378534 | 0.76 | MAPT (0.50) | NOTUMTDP1CA12CA1CA2 | |
| SCHEMBL29379236 | 0.75 | NOTUM (0.47) | NOTUM | |
| Formic Acid SCHEMBL28102282 | 0.73 | NOTUM (0.55) | NOTUM | |
| SCHEMBL28025989 | 0.70 | NOTUM (0.65) | NOTUMKCNH2 | |
| SCHEMBL5007470 | 0.69 | HTT (0.51) | NOTUMKCNH2PTGS2TDP1CASR | |
| SCHEMBL29378354 | 0.68 | NOTUM (0.47) | NOTUMKCNH2 | |
| SCHEMBL28646619 | 0.67 | NOTUM (0.63) | NOTUMKCNH2PTGS2 | |
| SCHEMBL30999699 | 0.67 | NPC1 (0.54) | NOTUMCASR | |
| SCHEMBL3318259 | 0.67 | NOTUM (0.58) | NOTUMKCNH2CASR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025104081-A1 | TRIAZOLE DERIVATIVES AND THEIR USE IN THE TREATMENT OF NEURODEGENERATIVE DISORDERS | REMYND N.V. (BE) | 2025-05-22 | — | — | WO | disclosed |