Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31589777 | 0.79 | APLNR (0.51) | KDM4EMAPTMEN1KMT2AALPL | |
| SCHEMBL31589339 | 0.77 | NNMT (0.65) | NNMTKDM4EMAPTMEN1KMT2A | |
| SCHEMBL31589389 | 0.75 | SMN1; SMN2 (0.44) | ALPLALDH1A1HTTLMNAL3MBTL1 | |
| SCHEMBL15004552 | 0.75 | NNMT (0.61) | NNMTMAPTHTTSMN1; SMN2HPGD | |
| SCHEMBL21467388 | 0.75 | NNMT (0.53) | NNMTKMT2AALDH1A1LMNAL3MBTL1 | |
| SCHEMBL19198279 | 0.74 | NNMT (0.56) | NNMTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL18896202 | 0.72 | NNMT (0.58) | NNMTKDM4EALDH1A1HTTL3MBTL1 | |
| SCHEMBL1544504 | 0.71 | NNMT (0.66) | NNMTKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL6770004 | 0.70 | LMNA (0.73) | KDM4EMAPTKMT2AALDH1A1HTT | |
| SCHEMBL10042096 | 0.70 | KDM4E (0.40) | KDM4EMAPTALPLALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025110780-A1 | NOVEL HETEROCYCLIC COMPOUNDS AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME AS DNA POLYMERASE THETA INHIBITORS FOR THE PREVENTION OR TREATMENT OF CANCER | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2025-05-30 | — | — | WO | disclosed |
| CN-120040437-A | Novel heterocyclic compound and pharmaceutical composition comprising same | 株式会社大熊制药 | 2025-05-27 | — | — | CN | disclosed |