Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31590763 | 0.81 | KDM4E (0.43) | ALDH1A1HPGDKDM4EGAALMNA | |
| SCHEMBL16309064 | 0.79 | SMN1; SMN2 (0.51) | SMN1; SMN2ALDH1A1HPGDRAB9ADRD2 | |
| SCHEMBL16309075 | 0.78 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1HPGDRAB9ADRD2 | |
| SCHEMBL24712976 | 0.77 | SMN1; SMN2 (0.49) | SMN1; SMN2ALDH1A1HPGDRAB9ADRD2 | |
| SCHEMBL12283713 | 0.75 | AAK1 (0.48) | SMN1; SMN2ALDH1A1HPGDRAB9ATSHR | |
| SCHEMBL16309072 | 0.74 | SMN1; SMN2 (0.49) | SMN1; SMN2ALDH1A1HPGDRAB9ADRD2 | |
| SCHEMBL26537904 | 0.74 | SMN1; SMN2 (0.49) | SMN1; SMN2ALDH1A1HPGDRAB9ADRD2 | |
| SCHEMBL18863880 | 0.74 | ALDH1A1 (0.52) | SMN1; SMN2ALDH1A1HPGDRAB9ADRD2 | |
| SCHEMBL25780650 | 0.74 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1HPGDRAB9ADRD2 | |
| SCHEMBL31056284 | 0.74 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1HPGDRAB9ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120040475-A | Compounds as WRN inhibitors and uses thereof | 南京圣和药业股份有限公司 | 2025-05-27 | — | — | CN | disclosed |