Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31056064 | 0.80 | L3MBTL1 (0.39) | SMN1; SMN2ALDH1A1HPGDCYP3A4CA12 | |
| SCHEMBL16309064 | 0.78 | SMN1; SMN2 (0.51) | SMN1; SMN2DRD2DRD4DRD3ALDH1A1 | |
| SCHEMBL16309075 | 0.76 | SMN1; SMN2 (0.50) | SMN1; SMN2DRD2DRD4DRD3ALDH1A1 | |
| SCHEMBL16309072 | 0.75 | SMN1; SMN2 (0.49) | SMN1; SMN2DRD2DRD4DRD3ALDH1A1 | |
| SCHEMBL26537904 | 0.75 | SMN1; SMN2 (0.49) | SMN1; SMN2DRD2DRD4DRD3ALDH1A1 | |
| SCHEMBL24712976 | 0.75 | SMN1; SMN2 (0.49) | SMN1; SMN2DRD2DRD4DRD3ALDH1A1 | |
| SCHEMBL18863880 | 0.75 | ALDH1A1 (0.52) | SMN1; SMN2DRD2DRD4DRD3ALDH1A1 | |
| SCHEMBL31205187 | 0.75 | DRD2 (0.48) | SMN1; SMN2DRD2DRD4DRD3ALDH1A1 | |
| SCHEMBL31280138 | 0.75 | SMN1; SMN2 (0.46) | SMN1; SMN2DRD2DRD4DRD3ALDH1A1 | |
| SCHEMBL25780650 | 0.75 | SMN1; SMN2 (0.46) | SMN1; SMN2DRD2DRD4DRD3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024178390-A1 | COVALENT MODIFIERS OF AKT1 AND USES THEREOF | TERREMOTO BIOSCIENCES, INC. (US) | 2024-08-29 | — | — | WO | disclosed |