Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | EPHB3 | P54753 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.36 |
| ▸ | SELL | P14151 | 1/20 | 0.35 |
| ▸ | SELP | P16109 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.35 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.33 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31589732 | 0.81 | SMN1; SMN2 (0.47) | KDM4EALDH1A1HPGDGAALMNA | |
| SCHEMBL1701947 | 0.73 | L3MBTL1 (0.40) | KDM4EALDH1A1L3MBTL1EPHB3NR4A3 | |
| SCHEMBL1290436 | 0.72 | EPHB3 (0.58) | KDM4EALDH1A1HPGDHSD17B10L3MBTL1 | |
| SCHEMBL28801140 | 0.70 | EPHB3 (0.43) | KDM4EHPGDL3MBTL1EPHB3NOTUM | |
| SCHEMBL1702440 | 0.70 | L3MBTL1 (0.40) | KDM4EALDH1A1L3MBTL1EPHB3NR4A3 | |
| SCHEMBL359281 | 0.67 | TYK2 (0.53) | KDM4EALDH1A1L3MBTL1PKMKMT2A | |
| SCHEMBL16646778 | 0.67 | L3MBTL1 (0.40) | KDM4EALDH1A1HPGDHSD17B10L3MBTL1 | |
| SCHEMBL25238938 | 0.66 | CYP1A2 (0.40) | KDM4EALDH1A1L3MBTL1GAAPKM | |
| SCHEMBL31056064 | 0.66 | L3MBTL1 (0.39) | KDM4EALDH1A1HPGDHSD17B10L3MBTL1 | |
| SCHEMBL3073610 | 0.66 | EPHB3 (0.56) | KDM4EALDH1A1HSD17B10L3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120040475-A | Compounds as WRN inhibitors and uses thereof | 南京圣和药业股份有限公司 | 2025-05-27 | — | — | CN | disclosed |