SCHEMBL31590141

SCHEMBL31590141

Cc1cc([SiH2]c2ccccc2)c(C)c(C)c1C

nearest known ligand 0.32

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
ALDH1A1 P00352 1/20 0.32
POLB P06746 1/20 0.32
MAPT P10636 1/20 0.32
PKM P14618 1/20 0.32
RAB9A P51151 1/20 0.32
KMT2A Q03164 1/20 0.32
TSHR P16473 1/20 0.31
ACHE P22303 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28823591 1.00 KDM4E (0.32) KDM4EMEN1ALDH1A1POLBMAPT
SCHEMBL28040867 0.83 TSHR (0.37) MAPTTSHRACHE
SCHEMBL27871135 0.82
SCHEMBL28040487 0.82 CYP1A2 (0.36) KDM4EMEN1ALDH1A1POLBMAPT
SCHEMBL28040456 0.78 TSHR (0.33) ALDH1A1MAPTRAB9ATSHRACHE
SCHEMBL989764 0.77 TRPA1 (0.38) MEN1ALDH1A1KMT2ATSHRACHE
SCHEMBL28040366 0.75 KDM4E (0.32) KDM4EMEN1ALDH1A1POLBMAPT
SCHEMBL28634226 0.75 TRPA1 (0.38) MEN1ALDH1A1POLBKMT2ATSHR
SCHEMBL988389 0.74 KDM4E (0.34) KDM4EMEN1ALDH1A1POLBMAPT
SCHEMBL2453373 0.73 TSHR (0.43) ALDH1A1TSHRACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120040771-A Hafnium hybridization carbon-rich polysiloxane flexible ablation material, preparation method and application thereof 四川大学 2025-05-27 CN disclosed