Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | EPHB3 | P54753 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31056284 | 0.80 | SMN1; SMN2 (0.46) | ERN1ALDH1A1SMN1; SMN2KDM4EHPGD | |
| SCHEMBL31150987 | 0.77 | L3MBTL1 (0.43) | L3MBTL1ALDH1A1SMN1; SMN2POLBMAPT | |
| SCHEMBL28650156 | 0.69 | FGFR4 (0.44) | L3MBTL1SMN1; SMN2KDM4EHSD17B10GAA | |
| SCHEMBL20482473 | 0.69 | CA1 (0.41) | L3MBTL1SMN1; SMN2POLBMAPTHSD17B10 | |
| SCHEMBL1702440 | 0.68 | L3MBTL1 (0.40) | L3MBTL1ALDH1A1SMN1; SMN2KDM4EPOLB | |
| SCHEMBL28801140 | 0.68 | EPHB3 (0.43) | L3MBTL1KDM4EHPGDMAPTMAPK1 | |
| SCHEMBL1701947 | 0.68 | L3MBTL1 (0.40) | L3MBTL1ALDH1A1SMN1; SMN2KDM4EPOLB | |
| SCHEMBL28630040 | 0.68 | L3MBTL1 (0.40) | L3MBTL1ALDH1A1SMN1; SMN2KDM4EPOLB | |
| SCHEMBL31205135 | 0.68 | ALDH1A1 (0.47) | L3MBTL1ALDH1A1KDM4EPOLBHPGD | |
| SCHEMBL22777570 | 0.67 | EIF4A3 (0.45) | L3MBTL1ALDH1A1SMN1; SMN2POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024178390-A1 | COVALENT MODIFIERS OF AKT1 AND USES THEREOF | TERREMOTO BIOSCIENCES, INC. (US) | 2024-08-29 | — | — | WO | disclosed |