Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.53 |
| ▸ | GAA | P10253 | 12/20 | 0.53 |
| ▸ | MAPT | P10636 | 8/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | CASP1 | P29466 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | CASP7 | P55210 | 1/20 | 0.53 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.44 |
| ▸ | TYMS | P04818 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10784314 | 0.87 | ALDH1A1 (0.52) | ALDH1A1GAAMAPTKDM4EMEN1 | |
| SCHEMBL31590791 | 0.84 | ALDH1A1 (0.67) | ALDH1A1GAAMAPTKDM4EMEN1 | |
| SCHEMBL8731853 | 0.81 | HRH3 (0.51) | ALDH1A1GAAMAPTKDM4EMEN1 | |
| SCHEMBL12682909 | 0.81 | ALDH1A1 (0.54) | ALDH1A1GAAMAPTKDM4EMEN1 | |
| SCHEMBL31476393 | 0.81 | ADRB3 (0.52) | ALDH1A1GAAMAPTKDM4EMEN1 | |
| SCHEMBL12956755 | 0.79 | ALDH1A1 (0.59) | ALDH1A1GAAMAPTKDM4EMEN1 | |
| SCHEMBL23128840 | 0.78 | HSD17B3 (0.52) | ALDH1A1GAAMAPTKDM4EMEN1 | |
| SCHEMBL10493943 | 0.78 | ATAD2 (0.53) | ALDH1A1GAAMAPTKDM4EMEN1 | |
| SCHEMBL8728886 | 0.78 | HDAC1 (0.52) | ALDH1A1GAAMAPTKDM4EMEN1 | |
| SCHEMBL12656517 | 0.78 | HDAC1 (0.53) | ALDH1A1GAAMAPTKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776482-A | Tetrahydroquinoline analogues for use in glaucoma treatment | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 1998-07-07 | — | — | US | claimed |