Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4574189 | 0.86 | OPRM1 (0.35) | MEN1KMT2APDE7ABACE1OPRM1 | |
| SCHEMBL4574763 | 0.82 | NPC1 (0.35) | MEN1KMT2APDE7ABACE1OPRM1 | |
| SCHEMBL1557008 | 0.81 | MEN1 (0.39) | MEN1CYP2C9KMT2APDE4APDE4B | |
| SCHEMBL6111097 | 0.81 | OPRM1 (0.33) | BACE1OPRM1 | |
| SCHEMBL2289999 | 0.80 | MEN1 (0.38) | MEN1CYP2C9KMT2APDE4APDE4B | |
| SCHEMBL7949441 | 0.80 | MEN1 (0.38) | MEN1CYP2C9KMT2APDE4APDE4B | |
| SCHEMBL2294184 | 0.80 | ADRA1A (0.43) | MEN1CYP2C9KMT2APDE4APDE4B | |
| SCHEMBL30168408 | 0.80 | MEN1 (0.38) | MEN1CYP2C9KMT2APDE4APDE4B | |
| SCHEMBL2288498 | 0.80 | ADRA1A (0.42) | MEN1CYP2C9KMT2APDE4APDE4B | |
| Ethylene SCHEMBL3968587 | 0.79 | MEN1 (0.37) | MEN1CYP2C9KMT2APDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2164825-A1 | DI(HETERO)ARYLCYCLOHEXANE DERIVATIVES, THEIR PREPARATION, THEIR USE AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | Sanofi-Aventis (FR) | 2010-03-24 | — | — | EP | disclosed |
| WO-2008148468-A1 | DI(HETERO)ARYLCYCLOHEXANE DERIVATIVES, THEIR PREPARATION, THEIR USE AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | SANOFI-AVENTIS (FR) | 2008-12-11 | — | — | WO | disclosed |