Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4574189 | 0.92 | OPRM1 (0.35) | NPC1ALDH1A1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL6111097 | 0.87 | OPRM1 (0.33) | OPRM1CA12CA1CA2CA9 | |
| SCHEMBL1558737 | 0.82 | MEN1 (0.34) | MEN1KMT2AOPRM1CA12CA1 | |
| SCHEMBL3159094 | 0.82 | MEN1 (0.38) | MEN1KMT2AOPRM1PDE7ABACE1 | |
| SCHEMBL2046481 | 0.78 | NPC1 (0.39) | NPC1ALDH1A1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL625354 | 0.78 | NPC1 (0.44) | NPC1ALDH1A1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL624164 | 0.77 | ADRA1A (0.41) | OPRM1 | |
| SCHEMBL18742441 | 0.77 | HDAC4 (0.41) | OPRM1LMNA | |
| SCHEMBL8106440 | 0.77 | PDE7A (0.36) | NPC1ALDH1A1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL10526403 | 0.77 | OPRM1 (0.39) | NPC1ALDH1A1RAB9ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119977947-A | PRMT5 inhibitor, pharmaceutical composition thereof and application of PRMT5 inhibitor in medicines | 广东东阳光药业股份有限公司 | 2025-05-13 | — | — | CN | disclosed |
| WO-2008050200-A1 | OXADIAZOLE COMPOUNDS AS CALCIUM CHANNEL ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2008-05-02 | — | — | WO | disclosed |