Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.39 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.36 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3159292 | 0.82 | GSTP1 (0.38) | CYP1A2ALDH1A1 | |
| SCHEMBL8675237 | 0.80 | BRD4 (0.39) | BRD4CREBBPPDGFRBPDGFRACYP1A2 | |
| Hydrochloric Acid SCHEMBL5170143 | 0.80 | GSTP1 (0.36) | CYP1A2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7569789 | 0.79 | PARP10 (0.40) | BRD4CREBBPPDGFRBPDGFRACYP1A2 | |
| Hydrochloric Acid SCHEMBL8675926 | 0.79 | BRD4 (0.38) | BRD4CREBBPPDGFRBPDGFRACYP1A2 | |
| SCHEMBL8675236 | 0.79 | BRD4 (0.38) | BRD4CREBBPPDGFRBPDGFRACYP1A2 | |
| SCHEMBL29366427 | 0.79 | PDCD1 (0.34) | BRD4CYP2A6NPC1ALDH1A1RAB9A | |
| SCHEMBL61908 | 0.79 | PDCD1 (0.34) | BRD4CYP2A6NPC1ALDH1A1RAB9A | |
| SCHEMBL5953421 | 0.78 | PARP10 (0.37) | BRD4CREBBPPDGFRBPDGFRACYP1A2 | |
| Hydrochloric Acid SCHEMBL7562438 | 0.77 | PARP10 (0.39) | BRD4CREBBPPDGFRBPDGFRACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0743317-B1 | Metallocenes comprising a heterocycle and catalysts containing them | BASELL POLYOLEFINE GMBH (DE) | 2002-08-28 | — | — | EP | disclosed |
| US-5840947-A | Organometallic compound | TARGOR GMBH (DE) | 1998-11-24 | — | — | US | disclosed |
| EP-0743317-A2 | Metallocenes comprising a heterocycle and catalysts containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-11-20 | — | — | EP | disclosed |