Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PYGL | P06737 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CCKBR | P32239 | 2/20 | 0.40 |
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
| ▸ | FNTB | P49356 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | CTSV | O60911 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30567233 | 1.00 | L3MBTL1 (0.46) | L3MBTL1TDP1RAB9ANPC1PPARG | |
| SCHEMBL25386644 | 1.00 | L3MBTL1 (0.46) | L3MBTL1TDP1RAB9ANPC1PPARG | |
| SCHEMBL25386639 | 1.00 | L3MBTL1 (0.46) | L3MBTL1TDP1RAB9ANPC1PPARG | |
| SCHEMBL30567142 | 0.88 | L3MBTL1 (0.40) | L3MBTL1TDP1RAB9ANPC1PYGL | |
| SCHEMBL31256610 | 0.80 | USP30 (0.43) | RAB9ANPC1PPARGPYGLHSD17B10 | |
| SCHEMBL25386852 | 0.77 | L3MBTL1 (0.50) | L3MBTL1TDP1RAB9ANPC1PPARG | |
| SCHEMBL26264484 | 0.76 | PPARG (0.45) | L3MBTL1TDP1RAB9APPARGPYGL | |
| SCHEMBL26264485 | 0.76 | PPARG (0.45) | L3MBTL1TDP1RAB9APPARGPYGL | |
| SCHEMBL25387355 | 0.76 | L3MBTL1 (0.54) | L3MBTL1TDP1KDM4ETP53BLM | |
| SCHEMBL25387353 | 0.76 | L3MBTL1 (0.54) | L3MBTL1TDP1KDM4ETP53BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250171404-A1 | PCNA INHIBITORS AND USES THEREOF | UNITED STATES GOVERNMENT | 2025-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250171404-A1 | PCNA INHIBITORS AND USES THEREOF | PCNA, MKI67, PCLAF | L3MBTL1 1817/4885TDP1 370/4885RAB9A 2797/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.