Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | FNTA | P49354 | 1/20 | 0.35 |
| ▸ | FNTB | P49356 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PYGL | P06737 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25386639 | 0.88 | L3MBTL1 (0.46) | L3MBTL1TDP1RAB9ANPC1KDM4E | |
| SCHEMBL30567233 | 0.88 | L3MBTL1 (0.46) | L3MBTL1TDP1RAB9ANPC1KDM4E | |
| SCHEMBL31595672 | 0.88 | L3MBTL1 (0.46) | L3MBTL1TDP1RAB9ANPC1KDM4E | |
| SCHEMBL25386644 | 0.88 | L3MBTL1 (0.46) | L3MBTL1TDP1RAB9ANPC1KDM4E | |
| SCHEMBL30567190 | 0.79 | L3MBTL1 (0.46) | L3MBTL1TDP1KDM4EALDH1A1HPGD | |
| SCHEMBL30567132 | 0.77 | MDM2 (0.41) | — | |
| SCHEMBL30567109 | 0.76 | MTNR1B (0.48) | TDP1KDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL25386852 | 0.73 | L3MBTL1 (0.50) | L3MBTL1TDP1RAB9ANPC1ALDH1A1 | |
| SCHEMBL31256610 | 0.71 | USP30 (0.43) | RAB9ANPC1HSD17B10USP30ALDH1A1 | |
| SCHEMBL7307013 | 0.69 | ADRB2 (0.44) | L3MBTL1TDP1KDM4EHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4490142-A2 | PCNA INHIBITORS AND USES THEREOF | City of Hope (US) | 2025-01-15 | — | — | EP | disclosed |
| WO-2023172880-A2 | PCNA INHIBITORS AND USES THEREOF | CITY OF HOPE (US) | 2023-09-14 | — | — | WO | disclosed |