Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | LMNA | P02545 | 7/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | BLM | P54132 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | LTA4H | P09960 | 2/20 | 0.43 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25387355 | 1.00 | L3MBTL1 (0.54) | L3MBTL1TDP1ALDH1A1LMNAHPGD | |
| SCHEMBL30567190 | 0.85 | L3MBTL1 (0.46) | L3MBTL1TDP1ALDH1A1LMNAHPGD | |
| SCHEMBL30567233 | 0.76 | L3MBTL1 (0.46) | L3MBTL1TDP1ALDH1A1LMNAHPGD | |
| SCHEMBL31595672 | 0.76 | L3MBTL1 (0.46) | L3MBTL1TDP1ALDH1A1LMNAHPGD | |
| SCHEMBL25386639 | 0.76 | L3MBTL1 (0.46) | L3MBTL1TDP1ALDH1A1LMNAHPGD | |
| SCHEMBL25386644 | 0.76 | L3MBTL1 (0.46) | L3MBTL1TDP1ALDH1A1LMNAHPGD | |
| SCHEMBL28447277 | 0.74 | LTA4H (0.49) | L3MBTL1LMNABLMLTA4H | |
| SCHEMBL25384740 | 0.73 | PTPN1 (0.46) | L3MBTL1TDP1ALDH1A1LMNAHPGD | |
| SCHEMBL25384735 | 0.73 | PTPN1 (0.46) | L3MBTL1TDP1ALDH1A1LMNAHPGD | |
| SCHEMBL28770107 | 0.72 | L3MBTL1 (0.60) | L3MBTL1TDP1ALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023172880-A2 | PCNA INHIBITORS AND USES THEREOF | CITY OF HOPE (US) | 2023-09-14 | — | — | WO | disclosed |