Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
| ▸ | MARK3 | P27448 | 1/20 | 0.47 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.47 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.47 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.47 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30958459 | 1.00 | L3MBTL1 (0.56) | L3MBTL1KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL17347025 | 0.90 | L3MBTL1 (0.53) | L3MBTL1KMT2AMEN1KDM4EACHE | |
| SCHEMBL6179129 | 0.88 | L3MBTL1 (0.56) | L3MBTL1KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL28247794 | 0.87 | L3MBTL1 (0.55) | L3MBTL1KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL30207773 | 0.87 | L3MBTL1 (0.55) | L3MBTL1KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL28247852 | 0.87 | L3MBTL1 (0.55) | L3MBTL1KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL28247204 | 0.87 | L3MBTL1 (0.55) | L3MBTL1KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL1746797 | 0.86 | KMT2A (0.76) | L3MBTL1KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL29651126 | 0.86 | KMT2A (0.76) | L3MBTL1KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL6179754 | 0.83 | L3MBTL1 (0.55) | L3MBTL1KMT2AMEN1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023183444-A1 | MODULATORS OF PROTEIN KINASES | VIBLIOME THERAPEUTICS, LLC (US) | 2023-09-28 | — | — | WO | disclosed |
| WO-2023183444-A1 | MODULATORS OF PROTEIN KINASES | VIBLIOME THERAPEUTICS, LLC (US) | 2023-09-28 | — | — | WO | disclosed |
| CN-114853784-B | Staurosporine compound and preparation method and application thereof | 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) | 2023-09-05 | — | — | CN | disclosed |
| CN-114853784-A | Staurosporine compound and preparation method and application thereof | 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) | 2022-08-05 | — | — | CN | disclosed |
| US-11136318-B2 | Processes for the preparation of aryl hydrocarbon receptor ligands | NORAMCO, LLC (US) | 2021-10-05 | — | — | US | disclosed |
| US-11136318-B2 | Processes for the preparation of aryl hydrocarbon receptor ligands | NORAMCO, LLC (US) | 2021-10-05 | — | — | US | disclosed |
| US-20210009579-A1 | PROCESSES FOR THE PREPARATION OF ARYL HYDROCARBON RECEPTOR LIGANDS | MERCACHEM PROCESS RESEARCH BV (NL) | 2021-01-14 | — | — | US | disclosed |
| US-20210009579-A1 | PROCESSES FOR THE PREPARATION OF ARYL HYDROCARBON RECEPTOR LIGANDS | MERCACHEM PROCESS RESEARCH BV (NL) | 2021-01-14 | — | — | US | disclosed |
| US-8273745-B2 | Polycyclic acid compounds useful as CRTH2 antagonists and antiallergic agents | ASTELLAS PHARMA INC (JP) | 2012-09-25 | — | — | US | disclosed |
| CN-102442941-A | Polycyclic acid compounds useful as crth2 antagonists and antiallergic agents | ASTELLAS PHARMA INC | 2012-05-09 | — | — | CN | disclosed |
| EP-2094662-B1 | POLYCYCLIC ACID COMPOUNDS USEFUL AS CRTH2 ANTAGONISTS AND ANTIALLERGIC AGENTS | ASTELLAS PHARMA INC (JP) | 2012-04-11 | — | — | EP | disclosed |
| CN-101636386-A | Polycyclic acid compounds useful as CRTH2 antagonists and antiallergic agents | ASTELLAS PHARMA INC | 2010-01-27 | — | — | CN | disclosed |
| US-20100009991-A1 | POLYCYCLIC ACID COMPOUNDS USEFUL AS CRTH2 ANTAGONISTS AND ANTIALLERGIC AGENTS | ASTELLAS PHARMA INC. (JP) | 2010-01-14 | — | — | US | disclosed |
| EP-2094662-A1 | POLYCYCLIC ACID COMPOUNDS USEFUL AS CRTH2 ANTAGONISTS AND ANTIALLERGIC AGENTS | Astellas Pharma Inc. (JP) | 2009-09-02 | — | — | EP | disclosed |
| WO-2008072784-A1 | POLYCYCLIC ACID COMPOUNDS USEFUL AS CRTH2 ANTAGONISTS AND ANTIALLERGIC AGENTS | ASTELLAS PHARMA INC. (JP) | 2008-06-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100009991-A1 | POLYCYCLIC ACID COMPOUNDS USEFUL AS CRTH2 ANTAGONISTS AND ANTIALLERGIC AGENTS | HRH2, HRH1, HRH4 | L3MBTL1 4881/4885KMT2A 2733/4885MEN1 3534/4885 |
| US-20210009579-A1 | PROCESSES FOR THE PREPARATION OF ARYL HYDROCARBON RECEPTOR LIGANDS | AHR, ARNT, INSR | L3MBTL1 2910/4885KMT2A 434/4885MEN1 4694/4885 |
| US-11136318-B2 | Processes for the preparation of aryl hydrocarbon receptor ligands | AHR, ARNT, INSR | L3MBTL1 2910/4885KMT2A 434/4885MEN1 4694/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.