Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.54 |
| ▸ | MAPT | P10636 | 7/20 | 0.54 |
| ▸ | MEN1 | O00255 | 6/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | HTT | P42858 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | RORC | P51449 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11037350 | 0.84 | ALDH1A1 (0.65) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL31596187 | 0.83 | TGM2 (0.59) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL8462703 | 0.81 | HTT (0.60) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL30725831 | 0.81 | HTT (0.60) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL18147758 | 0.79 | MAPT (0.62) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL18147762 | 0.79 | MAPT (0.62) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL12512971 | 0.79 | ALDH1A1 (0.71) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL3004695 | 0.78 | HTT (0.69) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL9836357 | 0.78 | MAPT (0.57) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL7581412 | 0.77 | SMN1; SMN2 (0.54) | ALDH1A1MAPTMEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120058736-A | FLT3 covalent inhibitor containing isoxazolo [5,4-b ] pyridine structure and preparation method and application thereof | 南京中医药大学 | 2025-05-30 | — | — | CN | disclosed |