Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.62 |
| ▸ | MEN1 | O00255 | 7/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.62 |
| ▸ | HTT | P42858 | 5/20 | 0.62 |
| ▸ | LMNA | P02545 | 4/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | RORC | P51449 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.48 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18147762 | 1.00 | MAPT (0.62) | MAPTKMT2AMEN1ALDH1A1HTT | |
| SCHEMBL2852173 | 0.87 | KMT2A (0.69) | MAPTKMT2AMEN1ALDH1A1HTT | |
| SCHEMBL2852168 | 0.87 | KMT2A (0.69) | MAPTKMT2AMEN1ALDH1A1HTT | |
| SCHEMBL30725831 | 0.85 | HTT (0.60) | MAPTKMT2AMEN1ALDH1A1HTT | |
| SCHEMBL8462703 | 0.85 | HTT (0.60) | MAPTKMT2AMEN1ALDH1A1HTT | |
| SCHEMBL9836357 | 0.85 | MAPT (0.57) | MAPTKMT2AMEN1ALDH1A1HTT | |
| SCHEMBL4686948 | 0.84 | MEN1 (0.54) | MAPTKMT2AMEN1ALDH1A1HTT | |
| SCHEMBL4686951 | 0.84 | MEN1 (0.54) | MAPTKMT2AMEN1ALDH1A1HTT | |
| SCHEMBL29074265 | 0.83 | KMT2A (0.64) | MAPTKMT2AMEN1ALDH1A1HTT | |
| SCHEMBL25433021 | 0.83 | RORC (0.60) | MAPTKMT2AMEN1ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11987568-B2 | Allosteric inhibitor of WEE1 kinase | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (US) | 2024-05-21 | — | — | US | disclosed |
| US-20230180761-A1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | CORTEVA AGRISCIENCE LLC (US) | 2023-06-15 | — | — | US | disclosed |
| US-11632957-B2 | Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto | CORTEVA AGRISCIENCE LLC (US) | 2023-04-25 | — | — | US | disclosed |
| US-20210309630-A1 | ALLOSTERIC INHIBITOR OF WEE1 KINASE | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. | 2021-10-07 | — | — | US | disclosed |
| US-20210106571-A1 | ISOTHIOCYANATE-ANDROGEN RECEPTOR INHIBITOR CONJUGATES FOR APOPTOSIS AND/OR FERROPTOSIS INDUCTION IN CANCER CELLS | WAYNE STATE UNIVERSITY (US) | 2021-04-15 | — | — | US | disclosed |
| US-20200196607-A1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2020-06-25 | — | — | US | disclosed |
| WO-2020028814-A1 | ALLOSTERIC INHIBITOR OF WEE1 KINASE | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (US) | 2020-02-06 | — | — | WO | disclosed |
| EP-3578543-A1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | Dow AgroSciences LLC (US) | 2019-12-11 | — | — | EP | disclosed |
| EP-3283459-B1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2019-05-22 | — | — | EP | disclosed |
| US-20190090488-A1 | Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto | DOW AGROSCIENCES LLC (US) | 2019-03-28 | — | — | US | disclosed |
| US-10219516-B2 | Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto | DOW AGROSCIENCES LLC (US) | 2019-03-05 | — | — | US | disclosed |
| EP-3283459-A1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | Dow Agrosciences LLC (US) | 2018-02-21 | — | — | EP | disclosed |
| US-20170339961-A1 | Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto | DOW AGROSCIENCES LLC (US) | 2017-11-30 | — | — | US | disclosed |
| US-9781935-B2 | Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto | DOW AGROSCIENCES LLC (US) | 2017-10-10 | — | — | US | disclosed |
| WO-2016168059-A1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2016-10-20 | — | — | WO | disclosed |
| US-20160304522-A1 | Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto | DOW AGROSCIENCES LLC (US) | 2016-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190090488-A1 | Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto | ACHE, DDT, MLYCD | MAPT 3431/4885KMT2A 2615/4885MEN1 1180/4885 |
| US-11632957-B2 | Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto | ACHE, DDT, MLYCD | MAPT 3431/4885KMT2A 2615/4885MEN1 1180/4885 |
| US-20210309630-A1 | ALLOSTERIC INHIBITOR OF WEE1 KINASE | WEE1, WEE2, PAXBP1 | MAPT 3332/4885KMT2A 581/4885MEN1 2076/4885 |
| US-11987568-B2 | Allosteric inhibitor of WEE1 kinase | WEE1, WEE2, PAXBP1 | MAPT 3332/4885KMT2A 581/4885MEN1 2076/4885 |
| US-20210106571-A1 | ISOTHIOCYANATE-ANDROGEN RECEPTOR INHIBITOR CONJUGATES FOR APOPTOSIS AND/OR FERROPTOSIS INDUCTION IN CANCER CELLS | AR, AIFM2, GSR | MAPT 3010/4885KMT2A 1536/4885MEN1 3714/4885 |
| US-20160304522-A1 | Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto | ACHE, DDT, MLYCD | MAPT 3431/4885KMT2A 2615/4885MEN1 1180/4885 |
| US-10219516-B2 | Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto | ACHE, DDT, MLYCD | MAPT 3431/4885KMT2A 2615/4885MEN1 1180/4885 |
| US-20230180761-A1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | ACHE, DDT, MLYCD | MAPT 3431/4885KMT2A 2615/4885MEN1 1180/4885 |
| US-20200196607-A1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | ACHE, DDT, MLYCD | MAPT 3431/4885KMT2A 2615/4885MEN1 1180/4885 |
| US-20170339961-A1 | Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto | ACHE, DDT, MLYCD | MAPT 3431/4885KMT2A 2615/4885MEN1 1180/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.