Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 12/20 | 0.46 |
| ▸ | NAMPT | P43490 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31599303 | 0.82 | NAMPT (0.42) | RORCNAMPTTP53MAPTSMN1; SMN2 | |
| SCHEMBL3047693 | 0.79 | GLA (0.52) | SMN1; SMN2MAPK1 | |
| SCHEMBL30565171 | 0.79 | SMN1; SMN2 (0.54) | NAMPTMAPTSMN1; SMN2MAPK1LMNA | |
| SCHEMBL4753910 | 0.79 | ALDH1A1 (0.64) | MAPTSMN1; SMN2 | |
| SCHEMBL30474440 | 0.77 | RORC (0.54) | RORCCA1CA2 | |
| SCHEMBL30565173 | 0.76 | WDR5 (0.43) | NAMPTSMN1; SMN2AR | |
| SCHEMBL31599309 | 0.76 | ACACB (0.46) | RORC | |
| SCHEMBL31599302 | 0.76 | ACACB (0.46) | RORC | |
| SCHEMBL31599291 | 0.75 | ACACB (0.36) | NAMPTTP53MAPTSMN1; SMN2LMNA | |
| SCHEMBL30065034 | 0.74 | TSHR (0.66) | RORCNAMPTSMN1; SMN2CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113072546-B | Five-membered heteroaromatic derivative and preparation method and application thereof | 广东东阳光药业股份有限公司 | 2025-05-30 | — | — | CN | disclosed |