Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 5/20 | 0.61 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.49 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | SNRNP200 | O75643 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
| ▸ | BRD2 | P25440 | 1/20 | 0.48 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.48 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9950840 | 0.86 | NPC1 (0.51) | MAPK14NPC1SMN1; SMN2RAB9ATP53 | |
| SCHEMBL24820991 | 0.83 | BRD4 (0.48) | MAPK14HRH3SMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL18951821 | 0.82 | SIGMAR1 (0.54) | TP53ALDH1A1KMT2AKDM4EBRD4 | |
| SCHEMBL29161591 | 0.81 | HRH3 (0.47) | MAPK14HRH3NPC1SMN1; SMN2RAB9A | |
| SCHEMBL5194377 | 0.80 | HRH3 (0.47) | HRH3NPC1SMN1; SMN2RAB9ATP53 | |
| SCHEMBL5448903 | 0.80 | MAPK14 (0.54) | MAPK14HRH3S1PR5NR4A2MAPT | |
| SCHEMBL5440765 | 0.79 | L3MBTL1 (0.52) | HRH3NPC1SMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL2177074 | 0.76 | MAPK14 (1.00) | MAPK14SMN1; SMN2MEN1ALDH1A1KMT2A | |
| SCHEMBL29821531 | 0.76 | BRD4 (0.56) | MAPK14SMN1; SMN2RAB9ATP53ALDH1A1 | |
| SCHEMBL27772274 | 0.74 | MAPT (0.63) | SMN1; SMN2RAB9AMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025111251-A1 | COMPOUNDS THAT INHIBIT POLO-LIKE KINASE 4 | EXELIXIS, INC. (US) | 2025-05-30 | — | — | WO | disclosed |