Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 2/20 | 0.46 |
| ▸ | BRD2 | P25440 | 1/20 | 0.46 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.46 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31599546 | 0.81 | MAPK14 (0.61) | HRH3BRD4BRD2BRD3BRDT | |
| SCHEMBL5440765 | 0.78 | L3MBTL1 (0.52) | HRH3L3MBTL1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL24820991 | 0.77 | BRD4 (0.48) | HRH3BRD4BRD2BRD3BRDT | |
| SCHEMBL18951821 | 0.76 | SIGMAR1 (0.54) | BRD4BRD2BRD3BRDTL3MBTL1 | |
| SCHEMBL5431537 | 0.74 | HRH3 (0.63) | HRH3BRD4BRD2BRD3BRDT | |
| SCHEMBL5442729 | 0.71 | L3MBTL1 (0.47) | HRH3L3MBTL1ALDH1A1RAB9AMAPT | |
| SCHEMBL16466424 | 0.71 | BRD4 (0.53) | BRD4BRD2BRD3BRDTALDH1A1 | |
| SCHEMBL1172641 | 0.71 | MGLL (0.59) | L3MBTL1RAB9AMAPTGAASMN1; SMN2 | |
| SCHEMBL5437583 | 0.69 | L3MBTL1 (0.45) | HRH3L3MBTL1ALDH1A1MAPTGAA | |
| SCHEMBL23168957 | 0.69 | MEN1 (0.44) | HRH3BRD4BRD2BRD3BRDT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117624160-A | Preparation method of cyclic substituted 2-pyridone compound | 安徽中医药大学 | 2024-03-01 | — | — | CN | disclosed |