Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 10/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 10/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 10/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 10/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9645499 | 1.00 | GABRA1 (0.42) | GABRA1GABRG2GABRB3GABRB2GABRB1 | |
| SCHEMBL5168262 | 0.80 | PDE4A (0.49) | GABRA1GABRG2GABRB3GABRB2GABRB1 | |
| SCHEMBL31599571 | 0.80 | PDE4A (0.49) | GABRA1GABRG2GABRB3GABRB2GABRB1 | |
| SCHEMBL8548467 | 0.80 | PDE4A (0.49) | GABRA1GABRG2GABRB3GABRB2GABRB1 | |
| SCHEMBL625934 | 0.78 | GABRA1 (0.53) | GABRA1GABRG2GABRB3GABRB2GABRB1 | |
| SCHEMBL625933 | 0.78 | GABRA1 (0.53) | GABRA1GABRG2GABRB3GABRB2GABRB1 | |
| SCHEMBL625935 | 0.78 | GABRA1 (0.53) | GABRA1GABRG2GABRB3GABRB2GABRB1 | |
| SCHEMBL25342763 | 0.77 | GABRA1 (0.58) | GABRA1GABRG2GABRB3GABRB2GABRB1 | |
| SCHEMBL11761840 | 0.77 | GABRA1 (0.58) | GABRA1GABRG2GABRB3GABRB2GABRB1 | |
| SCHEMBL16992765 | 0.77 | MAPT (0.46) | GABRA1GABRG2GABRB3GABRB2GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512020-A1 | PROCESS FOR PREPARING HOMOCHIRAL AMINES AND PROCESS FOR PREPARING INTERMEDIATES FOR THE PREPARATION THEREOF | Nobel Chemicals AB (SE) | 1992-11-11 | — | — | EP | claimed |
| WO-1991010642-A1 | PROCESS FOR PREPARING HOMOCHIRAL AMINES AND PROCESS FOR PREPARING INTERMEDIATES FOR THE PREPARATION THEREOF, AND THE INTERMEDIATES PREPARED IN ACCORDANCE WITH THIS PROCESS | NOBEL CHEMICALS AB (SE) | 1991-07-25 | — | — | WO | claimed |
| EP-0512020-A1 | PROCESS FOR PREPARING HOMOCHIRAL AMINES AND PROCESS FOR PREPARING INTERMEDIATES FOR THE PREPARATION THEREOF | Nobel Chemicals AB (SE) | 1992-11-11 | — | — | EP | disclosed |
| WO-1991010642-A1 | PROCESS FOR PREPARING HOMOCHIRAL AMINES AND PROCESS FOR PREPARING INTERMEDIATES FOR THE PREPARATION THEREOF, AND THE INTERMEDIATES PREPARED IN ACCORDANCE WITH THIS PROCESS | NOBEL CHEMICALS AB (SE) | 1991-07-25 | — | — | WO | disclosed |