⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16469032 | 0.71 | — | — | |
| SCHEMBL10118598 | 0.60 | — | — | |
| SCHEMBL423198 | 0.59 | — | — | |
| SCHEMBL31600086 | 0.59 | LMNA (0.32) | — | |
| SCHEMBL29729074 | 0.58 | — | — | |
| SCHEMBL31705525 | 0.57 | — | — | |
| SCHEMBL19743911 | 0.57 | — | — | |
| Hydrochloric Acid SCHEMBL30464867 | 0.57 | — | — | |
| SCHEMBL106441 | 0.57 | — | — | |
| SCHEMBL8568699 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025111547-A1 | 2,3-DIHYDROPYROLLOPYRIDINE CARBOXAMIDE COMPOUNDS AND METHODS OF USE THEREOF | RGENTA THERAPEUTICS, INC. (US) | 2025-05-30 | — | — | WO | disclosed |