Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31497245 | 0.83 | SMPD3 (0.40) | KDM4EALDH1A1HPGDHSD17B10SMPD3 | |
| SCHEMBL26664258 | 0.83 | RXFP1 (0.45) | KDM4EALDH1A1HPGDHSD17B10SMPD3 | |
| SCHEMBL31082622 | 0.81 | LMNA (0.41) | KDM4EALDH1A1HPGDHSD17B10SMPD3 | |
| SCHEMBL26664189 | 0.78 | RXFP1 (0.35) | KMT2AMEN1KDM4EALDH1A1HPGD | |
| SCHEMBL25151527 | 0.77 | TDP1 (0.47) | KMT2AMEN1KDM4EALDH1A1HPGD | |
| SCHEMBL16598636 | 0.77 | GABRA2 (0.38) | KMT2AMEN1KDM4EALDH1A1HPGD | |
| SCHEMBL21818768 | 0.74 | KMT2A (0.48) | KMT2AMEN1KDM4EALDH1A1HPGD | |
| SCHEMBL17857303 | 0.74 | KDM4E (0.43) | KMT2AMEN1KDM4EALDH1A1HPGD | |
| SCHEMBL4251317 | 0.72 | KDM4E (0.44) | KMT2AMEN1KDM4EALDH1A1HPGD | |
| SCHEMBL25417903 | 0.71 | KDM4E (0.41) | KMT2AMEN1KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025111547-A1 | 2,3-DIHYDROPYROLLOPYRIDINE CARBOXAMIDE COMPOUNDS AND METHODS OF USE THEREOF | RGENTA THERAPEUTICS, INC. (US) | 2025-05-30 | — | — | WO | disclosed |