Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | KLK7 | P49862 | 1/20 | 0.46 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 8/20 | 0.46 |
| ▸ | CTSS | P25774 | 2/20 | 0.44 |
| ▸ | SYK | P43405 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 3/20 | 0.43 |
| ▸ | CTSL | P07711 | 3/20 | 0.43 |
| ▸ | YAP1 | P46937 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31604809 | 0.92 | YAP1 (0.49) | PPARAKLK7KLK5P2RX7CTSS | |
| SCHEMBL21753086 | 0.80 | NAMPT (0.52) | CTSKCTSLYAP1 | |
| SCHEMBL21248948 | 0.79 | SYK (0.49) | P2RX7SYKCTSLYAP1 | |
| SCHEMBL31646594 | 0.79 | PPARA (0.48) | PPARAKLK7KLK5CTSSSYK | |
| SCHEMBL20158205 | 0.78 | YAP1 (0.49) | KLK7KLK5P2RX7CTSSSYK | |
| SCHEMBL28743990 | 0.78 | YAP1 (0.49) | KLK7KLK5P2RX7CTSSSYK | |
| SCHEMBL18459337 | 0.77 | YAP1 (0.48) | P2RX7CTSSCTSKYAP1 | |
| SCHEMBL5099423 | 0.77 | YAP1 (0.52) | P2RX7YAP1 | |
| SCHEMBL5099437 | 0.77 | YAP1 (0.52) | P2RX7YAP1 | |
| SCHEMBL5099430 | 0.77 | YAP1 (0.52) | P2RX7YAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025111414-A1 | TRPM3-MODULATING BENZOFURAN DERIVATIVES | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2025-05-30 | — | — | WO | disclosed |