Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.49 |
| ▸ | BACE1 | P56817 | 2/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 8/20 | 0.46 |
| ▸ | YAP1 | P46937 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2826301 | 0.82 | NAMPT (0.61) | SYKNAMPTMEN1MAPTKMT2A | |
| SCHEMBL29290594 | 0.82 | GPR119 (0.48) | SYKBACE1CTSLP2RX7L3MBTL1 | |
| SCHEMBL21248989 | 0.82 | SYK (0.50) | SYKBACE1CTSLP2RX7YAP1 | |
| SCHEMBL478953 | 0.81 | KYNU (0.44) | SYKBACE1CTSLP2RX7YAP1 | |
| SCHEMBL478951 | 0.81 | KYNU (0.44) | SYKBACE1CTSLP2RX7YAP1 | |
| SCHEMBL29940905 | 0.81 | SYK (0.54) | SYKBACE1CTSLP2RX7 | |
| SCHEMBL15898105 | 0.81 | SYK (0.49) | SYKBACE1CTSLP2RX7YAP1 | |
| SCHEMBL24392263 | 0.81 | NAMPT (0.51) | SYKNAMPTMEN1MAPTKMT2A | |
| SCHEMBL31604809 | 0.80 | YAP1 (0.49) | SYKCTSLP2RX7YAP1 | |
| SCHEMBL18930424 | 0.80 | ABCB1 (0.47) | SYKNAMPTYAP1L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3752498-A1 | SOMATOSTATIN MODULATORS AND USES THEREOF | Crinetics Pharmaceuticals, Inc. (US) | 2020-12-23 | — | — | EP | disclosed |
| WO-2019157458-A1 | SOMATOSTATIN MODULATORS AND USES THEREOF | Crinetics Pharmaceuticals, Inc. (US) | 2019-08-15 | — | — | WO | disclosed |